Deciphering Diversities: Renal Asian Genetics Network (DRAGoN)
About the Deciphering Diversities: Renal Asian Genetics Network (DRAGoN)
DRAGoN stands for “Deciphering Diversities: Renal Asian Genetics Network”. It is a research consortium based in National University of Singapore, set up to investigate glomerular and proteinuric diseases in Asians. The network consists of nephrologists, paediatricians, pathologists scientists and biostatisticians.
Why is DRAGoN set up?
Primary glomerular disease, including focal segmental glomerulosclerosis (FSGS), is a common cause of renal failure in adults and children worldwide. Current treatment strategies are largely empirical and involve the use of immunosuppressive drugs which are often non-targeted, toxic and expensive. Yet, response rates are not always desirable. To date, more than 50 genes are known to cause proteinuric or familial haematuric diseases. Many of these are traditionally monogenic diseases ...